Understanding Unusual Glycogen in Lung Cancer Growth
Official title: Aberrant Glycogen in Lung Adenocarcinoma Tumorigenesis
Funded at University of Florida · NIH-11109727 · Data updated 2026-11-12
This project explores how unusual glycogen, a type of sugar storage, contributes to the growth of lung adenocarcinoma, the most common type of lung cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $531,350 |
| NIH project number | 5R01CA266004-05 |
| Project ID | NIH-11109727 on NIH RePORTER |
Who could benefit from this research
✓Could help
This foundational research is focused on understanding the biology of lung adenocarcinoma and does not directly involve patient participation at this stage.
✕Less likely to help
Patients seeking immediate new treatments or clinical trial opportunities would not directly benefit from this basic science research.
What this research studies
Lung adenocarcinoma is a serious type of lung cancer, and for many patients, current treatments don't offer a high chance of long-term survival. We need to find new ways to understand how this cancer grows so we can develop more effective, personalized treatments. Our team has found that a sugar storage molecule called glycogen behaves unusually in lung adenocarcinoma cells, and we've developed a special imaging technique to see this glycogen in great detail. We believe that by understanding these unique glycogen patterns and the proteins involved, we can uncover new targets for therapies that could specifically attack lung cancer cells.
Why it matters
Potential benefit: If successful, this work could lead to new ways to identify lung adenocarcinoma earlier and develop more targeted treatments for patients.
How similar studies have gone: Previous studies, including our own preliminary work, have shown that glycogen plays an important role in lung tumor progression, suggesting this is a promising area for further investigation.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Sun, Ramon C. — University of Florida
- Study coordinator: Sun, Ramon C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.