Understanding Type 1 Diabetes Progression
Project 1
This research aims to understand how the immune system, insulin-producing cells, and other pancreas cells work together to cause Type 1 Diabetes.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11091582 on NIH RePORTER |
What this research studies
Our bodies' immune system sometimes mistakenly attacks healthy cells, as seen in Type 1 Diabetes (T1D). This project explores how the immune system, the cells that make insulin (beta cells), and other pancreas cells contribute to T1D. We believe that stress in beta cells might trigger inflammation, leading to immune cells attacking and destroying them. Using advanced imaging and cell analysis, we will look closely at pancreas samples from donors to see how immune cells interact with and affect different types of pancreas cells during the disease.
Who could benefit from this research
Good fit: This foundational research is relevant for individuals living with Type 1 Diabetes or those at risk, as it seeks to uncover the root causes of the disease.
Not a fit: Patients seeking immediate new treatments or clinical trial participation would not directly benefit from this basic science research.
Why it matters
Potential benefit: This work could lead to a deeper understanding of how Type 1 Diabetes develops, potentially paving the way for new ways to prevent or treat the condition.
How similar studies have performed: This project builds upon recent evidence from other groups and the researchers' own work, suggesting a combined approach to understanding Type 1 Diabetes.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Atkinson, Mark a. — University of Florida
- Study coordinator: Atkinson, Mark a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.