NIH-funded research NIH-funded research

Understanding tumor ecology through mathematical modeling

Official title: Core 1: Mathematical Core

Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-10930176 · Data updated 2026-11-12

This study is looking at how tumors grow and change during cancer treatment by using math models to better understand how different types of cells interact, which can help improve care for patients like you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst
NIH-funded
Lab location1 site (Tampa, United States)
Project startSeptember 15, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$311,332
NIH project number5U54CA274507-02
Project IDNIH-10930176 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with various types of cancer who are undergoing treatment.

Less likely to help

Patients with non-cancerous conditions or those not currently receiving cancer treatment may not benefit from this research.

What this research studies

This research focuses on the changes in tumor ecology during cancer initiation, progression, and treatment by utilizing mathematical models. These models help bridge gaps in clinical and experimental data, allowing researchers to study complex interactions at various biological scales, from molecules to tissues. By developing spatial agent-based models, the research aims to capture the diversity of cell types and their interactions within tumors, providing insights that are difficult to obtain through traditional experimental methods. The ultimate goal is to enhance our understanding of tumor behavior and treatment responses in patients.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for cancer treatment by providing a deeper understanding of tumor dynamics.

How similar studies have gone: Other research has shown promise in using mathematical modeling to understand cancer dynamics, indicating that this approach could yield valuable insights.

Where this research is happening

  • H. Lee Moffitt Cancer Ctr & Res Inst
    Tampa, United States
    Active

Researchers

  • Principal investigator: Anderson, Alexander Robertson Allan — H. Lee Moffitt Cancer Ctr & Res Inst
  • Study coordinator: Anderson, Alexander Robertson Allan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.