Understanding tuberculosis trends in South Africa over ten years

Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohort

['FUNDING_R01'] · WITS HEALTH CONSORTIUM (PTY), LTD · NIH-10817724

This study is looking at how tuberculosis (TB) affects people in South Africa over ten years, focusing on their health, where they live, and their HIV status, to find better ways to treat TB and improve care for patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWITS HEALTH CONSORTIUM (PTY), LTD (nih funded)
Locations1 site (PARKTOWN, SOUTH AFRICA)
Trial IDNIH-10817724 on ClinicalTrials.gov

What this research studies

This research investigates the tuberculosis (TB) epidemic in South Africa by creating a ten-year cohort of TB patients. It aims to track patients' health outcomes, spatial locations, and HIV status using a national database of laboratory results. By analyzing this data, the research seeks to identify key factors affecting TB care and evaluate the impact of HIV treatment and new diagnostic tools on TB incidence. Patients will be monitored over a decade to provide insights into effective TB control strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with tuberculosis in South Africa, particularly those with co-infection of HIV.

Not a fit: Patients who do not have tuberculosis or are not located in South Africa may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved TB control strategies and ultimately reduce TB incidence and mortality in South Africa.

How similar studies have performed: Previous research has shown success in using longitudinal cohorts and spatial data to improve disease control strategies, indicating that this approach is promising.

Where this research is happening

PARKTOWN, SOUTH AFRICA

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Infectious Disease Pathway, Infectious Diseases, Infectious Disorder, Communicable Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.