Understanding tuberculosis trends in South Africa over ten years
Official title: Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohort
Funded at Wits Health Consortium (Pty), LTD · NIH-10817724 · Data updated 2026-11-12
This study is looking at how tuberculosis (TB) affects people in South Africa over ten years, focusing on their health, where they live, and their HIV status, to find better ways to treat TB and improve care for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wits Health Consortium (Pty), LTD NIH-funded |
| Lab location | 1 site (Parktown, South Africa) |
| Project start | April 13, 2020 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $313,617 |
| NIH project number | 5R01AI152126-05 |
| Project ID | NIH-10817724 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with tuberculosis in South Africa, particularly those with co-infection of HIV.
✕Less likely to help
Patients who do not have tuberculosis or are not located in South Africa may not benefit from this research.
What this research studies
This research investigates the tuberculosis (TB) epidemic in South Africa by creating a ten-year cohort of TB patients. It aims to track patients' health outcomes, spatial locations, and HIV status using a national database of laboratory results. By analyzing this data, the research seeks to identify key factors affecting TB care and evaluate the impact of HIV treatment and new diagnostic tools on TB incidence. Patients will be monitored over a decade to provide insights into effective TB control strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved TB control strategies and ultimately reduce TB incidence and mortality in South Africa.
How similar studies have gone: Previous research has shown success in using longitudinal cohorts and spatial data to improve disease control strategies, indicating that this approach is promising.
Where this research is happening
-
Wits Health Consortium (Pty), LTD
Parktown, South Africa Active
Researchers
- Principal investigator: Scott, Lesley — Wits Health Consortium (Pty), LTD
- Study coordinator: Scott, Lesley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.