Understanding treatment outcomes in Hispanic patients with inflammatory bowel diseases
Official title: Comparative effectiveness research in Hispanic patients with inflammatory bowel diseases
Funded at University of California, San Diego · NIH-11013383 · Data updated 2026-11-12
This study looks at how well treatments work for Hispanic patients with inflammatory bowel diseases like Crohn’s and ulcerative colitis, and it aims to understand how social factors and biology affect their health outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | January 18, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $591,209 |
| NIH project number | 5R01DK135937-02 |
| Project ID | NIH-11013383 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Hispanic individuals diagnosed with inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis.
✕Less likely to help
Patients who do not identify as Hispanic or those without a diagnosis of inflammatory bowel diseases may not benefit from this research.
What this research studies
This research investigates the treatment outcomes and disease patterns of Hispanic patients suffering from inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis. By utilizing large-scale epidemiologic studies and real-world data, the research aims to identify the social and biological factors that influence health outcomes in this underrepresented population. The study seeks to provide insights into how social determinants of health affect the management and effectiveness of treatments for IBD in Hispanic patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better health outcomes for Hispanic patients with inflammatory bowel diseases.
How similar studies have gone: Other research has shown success in understanding treatment outcomes in diverse populations, but this specific focus on Hispanic patients with IBD is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Singh, Siddharth — University of California, San Diego
- Study coordinator: Singh, Siddharth
Related research
Other NIH-funded projects on the same topics.
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Comparative care for IBD in Hispanic patients
A Mayo Clinic Arizona team will study how Crohn’s disease and ulcerative colitis progress and respond to treatments in Hispanic patients using real-world data.
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Understanding why some people with inflammatory bowel disease fail therapy
A physician-scientist at UNC is pursuing why inflammatory bowel disease treatment stops working so therapies can be kept effective longer.
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Celiac and IBD: unlocking how genes influence disease with DNA methylation
A research project aims to use genetic and epigenetic clues to better understand why celiac disease and inflammatory bowel disease affect people differently and how they respond to treatment.
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How genes and DNA changes influence celiac disease and inflammatory bowel disease
This project looks for DNA changes that alter gene activity to help predict risk, severity, and treatment response for people with celiac disease and inflammatory bowel disease.
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Understanding what triggers inflammation in inflammatory bowel diseases
This study is looking at what causes inflammation in people with Crohn's disease and ulcerative colitis who are feeling really well, to help find ways to keep them healthy and prevent flare-ups in the future.
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Finding ways to block bacterial enzymes that worsen inflammatory bowel diseases
This project looks for new ways to treat inflammatory bowel diseases like Crohn's and ulcerative colitis by targeting specific enzymes made by gut bacteria.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.