Understanding treatment outcomes for older adults with overactive bladder

Risk determination and prognostication for older and frail older adults undergoing advanced treatments for overactive bladder

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11073108

This study is looking at how older adults with overactive bladder respond to different advanced treatments, like injections and nerve stimulation, to find out what works best for them and to help doctors make better choices for their care.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11073108 on ClinicalTrials.gov

What this research studies

This research investigates how older and frail adults respond to advanced treatments for overactive bladder, including onabotulinumtoxinA, peripheral tibial nerve stimulation, and sacral neuromodulation. The study aims to identify the effectiveness and potential complications of these treatments specifically in this vulnerable population, which has been underrepresented in previous studies. By analyzing treatment outcomes, the researchers hope to develop a personalized prognostic tool that can guide clinicians in making better treatment decisions for older patients. This approach seeks to ensure that older adults receive appropriate care tailored to their unique health needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 65 and above who are experiencing refractory overactive bladder.

Not a fit: Patients under the age of 65 or those without overactive bladder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for older adults suffering from overactive bladder.

How similar studies have performed: While there has been extensive research on these treatments in younger populations, this study addresses a significant gap in knowledge regarding older adults, making it a novel approach.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.