Understanding treatment outcomes for older adults with overactive bladder

Determinants of outcomes for older and frail older adults with refractory overactive bladder

NIH-funded research University of California, San Francisco · NIH-10912086

This study is looking at how older adults with overactive bladder respond to new treatments, like injections and nerve stimulation, to find out which options work best and are safest for them, so they can get the right care for their needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10912086 on NIH RePORTER

What this research studies

This research investigates how older and frail adults respond to advanced treatments for overactive bladder, specifically focusing on therapies like onabotulinumtoxinA, peripheral tibial nerve stimulation, and sacral neuromodulation. The study aims to identify the effectiveness and potential complications of these treatments in this vulnerable population, which has been underrepresented in previous research. By analyzing treatment outcomes, the researchers hope to develop a personalized prognostic tool that can guide better treatment decisions for older patients. This approach seeks to ensure that older adults receive appropriate care tailored to their specific health needs.

Who could benefit from this research

Good fit: Ideal candidates for this research are older and frail adults experiencing refractory overactive bladder.

Not a fit: Patients who are younger or do not have overactive bladder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and outcomes for older adults suffering from overactive bladder.

How similar studies have performed: Previous research has shown success in understanding treatment outcomes in younger populations, but this approach is novel for older adults.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.