Understanding toxins from harmful algal blooms in freshwater
Shifting paradigms to emerging toxins in freshwater cyanobacterial blooms
This study is looking into the harmful effects of certain toxins produced by blue-green algae in our lakes and rivers, especially how they might affect our liver, kidneys, and brain, so we can better understand and keep our water safe for everyone.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10912318 on NIH RePORTER |
What this research studies
This research investigates the harmful algal blooms caused by cyanobacteria in freshwater systems, focusing on the toxic compounds they produce, particularly microcystins and newly discovered cytotoxins. The study aims to analyze the effects of these toxins on human health, especially their impact on the liver, kidneys, and brain. By examining environmental samples from lakes and water bodies, the research seeks to identify and characterize these emerging toxins, which could lead to better understanding and management of water safety. The approach includes collaboration with industry partners to explore the potency and effects of these toxins.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in areas affected by freshwater algal blooms or those who consume water from contaminated sources.
Not a fit: Patients who do not reside near freshwater systems or are not exposed to algal blooms may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved safety measures for drinking water and recreational activities, ultimately protecting public health.
How similar studies have performed: Previous research has shown success in identifying and managing toxins from algal blooms, but the specific focus on newly discovered cytotoxins represents a novel approach.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Bertin, Matthew John — Case Western Reserve University
- Study coordinator: Bertin, Matthew John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.