Understanding tissue damage and healing in Celiac Disease
Tissue destruction and healing in Celiac Disease
This study is looking into why some people with Celiac Disease still have symptoms and nutrient issues even when they stick to a gluten-free diet, and it aims to find ways to help them heal better by understanding the role of gut bacteria and other factors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10893380 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms behind tissue destruction and healing in individuals with Celiac Disease, particularly those who struggle to maintain a gluten-free diet. It aims to explore why some patients experience persistent symptoms and nutrient deficiencies despite adhering to dietary guidelines. By analyzing the role of the microbiome and other factors, the study seeks to uncover the complexities of Celiac Disease and improve patient outcomes. The research involves collecting data from patients to better understand their unique clinical presentations and healing processes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Celiac Disease, particularly those experiencing ongoing symptoms despite following a gluten-free diet.
Not a fit: Patients who do not have Celiac Disease or those who are able to maintain a strict gluten-free diet without complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for Celiac Disease, enhancing the quality of life for patients.
How similar studies have performed: Previous research has shown promise in understanding the complexities of Celiac Disease, but this study aims to address specific gaps that have not been fully explored.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Jabri, Bana — University of Chicago
- Study coordinator: Jabri, Bana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.