Understanding tiny cell messengers for Brittle Diabetes Mellitus
Multi-omics profiling of individual exosomes for origin-tracing, biomarker discovery, and biological function characterization
This project is creating a new way to look closely at tiny particles from our cells, called exosomes, to better understand and find new ways to help people with Brittle Diabetes Mellitus.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wellsim Biomedical Technologies, INC. NIH-funded |
| Lab location | 1 site (San Jose, UNITED STATES) |
| Project ID | NIH-11144343 on NIH RePORTER |
What this research studies
Our bodies contain tiny messengers called extracellular vesicles (EVs), or exosomes, which carry important information about our health. Currently, it's hard to study these individual exosomes to see their unique details, especially their genetic messages. This project is building a new technology that can look at both the surface and the genetic information of individual exosomes from blood samples. This advanced tool will help us discover new signs of disease and develop more precise treatments for conditions like Brittle Diabetes Mellitus.
Who could benefit from this research
Good fit: This foundational technology development is aimed at ultimately benefiting patients living with Brittle Diabetes Mellitus.
Not a fit: Patients without Brittle Diabetes Mellitus would not directly benefit from the specific disease insights gained from this particular technology.
Why it matters
Potential benefit: If successful, this technology could lead to earlier and more accurate diagnoses and more targeted treatments for Brittle Diabetes Mellitus.
How similar studies have performed: While some techniques exist for analyzing exosome surfaces, this project is exploring a largely new area by focusing on the genetic material within individual exosomes.
Where this research is happening
San Jose, UNITED STATES
- Wellsim Biomedical Technologies, INC. — San Jose, United States (Active)
Researchers
- Principal investigator: Chen, Yuchao — Wellsim Biomedical Technologies, INC.
- Study coordinator: Chen, Yuchao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.