Understanding thinking and learning differences in Latino children treated for leukemia
An Integrative Approach to Evaluate Neurocognitive Disparities in Latinos Undergoing Treatment for Childhood Leukemia.
This project looks at how childhood acute lymphoblastic leukemia and its treatment affect thinking, memory, school, and economic outcomes for Latino children and survivors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11126043 on NIH RePORTER |
What this research studies
You or your child would be followed from diagnosis through seven years after treatment with detailed tests of thinking, memory, attention, and school functioning. The team will use the ongoing REDIAL cohort and perform deep neurocognitive testing in about 400 children treated for ALL, with more than half of participants being Latino. Researchers will combine clinical records, socioeconomic and cultural information, and biological data including genetic ancestry to see what factors relate to thinking and learning problems. The goal is to understand why Latino survivors may experience different long-term cognitive and educational outcomes than non-Latino survivors.
Who could benefit from this research
Good fit: Children diagnosed with acute lymphoblastic leukemia and survivors followed up to seven years after diagnosis, especially Latino children and young adults treated for childhood ALL, are the ideal participants.
Not a fit: People without a history of childhood ALL, those treated for other cancers, or individuals far beyond the study's follow-up window are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could help tailor follow-up care, educational support, and interventions to reduce thinking and learning problems for Latino childhood leukemia survivors.
How similar studies have performed: Prior research has linked genetic ancestry to relapse risk and treatment neurotoxicity, but few large studies have combined long-term neurocognitive testing with socioeconomic and cultural data specifically in Latino survivors, so this work builds on earlier findings with a more comprehensive approach.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Raghubar, Kimberly Pauline — Baylor College of Medicine
- Study coordinator: Raghubar, Kimberly Pauline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.