Understanding the use and effects of antipsychotic medications in children and adolescents
Official title: Real-world, national evidence on the predictors and consequences of pediatric antipsychotic use
Funded at Trustees of Indiana University · NIH-10998448 · Data updated 2026-11-12
This study looks at how well antipsychotic medications work for kids and teens under 17, especially those with conditions like ADHD and autism, by analyzing a large group of over 46,000 young people to see what factors influence starting these medications and how they compare to other treatments in keeping kids out of the hospital.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 1F31MH134597-01A1 |
| Project ID | NIH-10998448 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adolescents under 17 years old who are currently prescribed antipsychotic medications or are considering such treatment.
✕Less likely to help
Patients who are not prescribed antipsychotic medications or are over the age of 17 may not receive direct benefits from this research.
What this research studies
This research investigates the characteristics and outcomes of children and adolescents who are prescribed antipsychotic medications, particularly focusing on those under 17 years of age. It aims to analyze a large dataset of over 46,000 youth to identify factors that lead to the initiation of these medications and to compare their effectiveness in reducing psychiatric hospitalizations against other treatment options. By examining demographic factors and specific conditions like ADHD and autism, the study seeks to provide insights into the real-world implications of antipsychotic use in the pediatric population.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better understanding of the risks and benefits of antipsychotic medications for children and adolescents.
How similar studies have gone: Previous research has highlighted concerns regarding the use of antipsychotics in youth, but this study aims to provide new insights by analyzing a large and diverse patient population.
Where this research is happening
-
Trustees of Indiana University
Bloomington, United States Active
Researchers
- Principal investigator: Sepe-Forrest, Linnea — Trustees of Indiana University
- Study coordinator: Sepe-Forrest, Linnea
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.