Understanding the structure of connective tissue using low-field magnetic resonance imaging
Quantitative Characterization of the Extra Cellular Matrix Components of Connective Tissue: Fingerprinting Macromolecular Components through Low-Field Magnetic Resonance
This study is looking at how to better understand and identify changes in connective tissues, like those affected by fibrosis, using a special type of imaging that doesn't require any invasive procedures, so we can help diagnose musculoskeletal conditions more accurately.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11074908 on NIH RePORTER |
What this research studies
This research focuses on the non-invasive quantification and characterization of extracellular matrix components in connective tissues, particularly in relation to fibrotic activity. By utilizing low-field magnetic resonance imaging, the study aims to identify and optimize biomarkers that can distinguish between healthy and diseased tissues. The approach involves developing composite gels that mimic connective tissue to enhance imaging techniques. Ultimately, this research seeks to improve diagnostic capabilities for conditions affecting musculoskeletal tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with connective tissue diseases or disorders, particularly those experiencing fibrotic changes.
Not a fit: Patients with acute injuries or conditions unrelated to connective tissue may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for assessing connective tissue disorders, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using low-field magnetic resonance for biological tissue characterization, indicating potential for success in this novel application.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Witherspoon, Velencia — Tulane University of Louisiana
- Study coordinator: Witherspoon, Velencia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.