Understanding the structure and dynamics of HIV proteins and their interactions
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-11076758
This study is looking at how certain proteins related to HIV work, using advanced tools to understand them better, which could help create new treatments for people living with HIV.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11076758 on ClinicalTrials.gov |
What this research studies
This research focuses on the expression, purification, and characterization of HIV-related proteins and their complexes. By utilizing advanced techniques such as X-ray crystallography and cryo-electron microscopy, the project aims to gain insights into the mechanisms of HIV biology. Patients may benefit from the development of novel therapeutic approaches informed by the structural understanding of these proteins. The research is conducted at the University of Utah, where state-of-the-art instrumentation and expertise are available to support these efforts.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals living with HIV or those at high risk of HIV infection.
Not a fit: Patients who are not affected by HIV or do not have risk factors for HIV infection may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for HIV infection and improve patient outcomes.
How similar studies have performed: Previous research has shown success in understanding HIV proteins through structural biology approaches, indicating a promising path for this project.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HILL, CHRISTOPHER P. — UNIVERSITY OF UTAH
- Study coordinator: HILL, CHRISTOPHER P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, Biology of HIV Infection