Understanding the safety of reducing unnecessary medications in older adults
Generating Evidence on Deprescribing Safety
This study is looking at how stopping certain medications can help older adults, especially those with Alzheimer's and other health issues, feel better and stay safe, while also listening to the experiences of patients, caregivers, and doctors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project ID | NIH-10883890 on NIH RePORTER |
What this research studies
This research investigates the process of deprescribing, which involves reducing or stopping medications that may not be beneficial for older adults, particularly those with multiple chronic conditions and Alzheimer's Disease. The study aims to identify and measure adverse drug withdrawal events that may occur when medications are discontinued, as these events are often not well documented. By focusing on the experiences of patients, caregivers, and healthcare professionals, the research seeks to improve the safety and effectiveness of medication management in older populations. The project will utilize advanced methods to capture data on medication changes and their effects on patients' health.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults with multiple chronic conditions, especially those diagnosed with Alzheimer's Disease or related dementias.
Not a fit: Patients who are not elderly or do not have multiple chronic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer medication practices for older adults, reducing the risks associated with polypharmacy and improving overall health outcomes.
How similar studies have performed: Previous research has shown that deprescribing can be beneficial, but this specific approach to measuring adverse drug withdrawal events is novel and has not been extensively tested.
Where this research is happening
Oakland, UNITED STATES
- Kaiser Foundation Research Institute — Oakland, United States (Active)
Researchers
- Principal investigator: Bayliss, Elizabeth a — Kaiser Foundation Research Institute
- Study coordinator: Bayliss, Elizabeth a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.