Understanding the safety and effectiveness of new cancer therapies using real-world data.
Official title: Real-World Data to Generate Real-World Evidence in Regulatory Decision-Making
Funded at Ecog-Acrin Medical Research Foundation · NIH-10913571 · Data updated 2026-11-12
This study is looking at how new cancer treatments work in everyday life, using real patient experiences and health records to find out who might benefit the most and how these treatments affect quality of life.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ecog-Acrin Medical Research Foundation NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $2,247,715 |
| NIH project number | 5U01FD007943-02 |
| Project ID | NIH-10913571 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include cancer patients who are receiving or considering new therapies and have diverse biological characteristics.
✕Less likely to help
Patients with conditions unrelated to cancer or those not receiving new cancer therapies may not benefit from this research.
What this research studies
This research focuses on gathering and analyzing real-world data to better understand how new cancer therapies perform outside of clinical trials. By leveraging advancements in genomics and electronic health records, the project aims to identify which patient populations may benefit most from these therapies. The study will also explore patient-reported outcomes to assess the quality of life impacts of these treatments. Ultimately, the goal is to generate real-world evidence that can inform regulatory decision-making regarding cancer therapies.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments, improving patient outcomes and quality of life.
How similar studies have gone: Other research has shown promise in using real-world data to inform treatment decisions, indicating that this approach could be effective.
Where this research is happening
-
Ecog-Acrin Medical Research Foundation
Philadelphia, United States Active
Researchers
- Principal investigator: Odwyer, Peter J — Ecog-Acrin Medical Research Foundation
- Study coordinator: Odwyer, Peter J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.