Understanding the safety and effectiveness of new cancer therapies using real-world data.

Real-World Data to Generate Real-World Evidence in Regulatory Decision-Making

NIH-funded research Ecog-Acrin Medical Research Foundation · NIH-10913571

This study is looking at how new cancer treatments work in everyday life, using real patient experiences and health records to find out who might benefit the most and how these treatments affect quality of life.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionEcog-Acrin Medical Research Foundation NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10913571 on NIH RePORTER

What this research studies

This research focuses on gathering and analyzing real-world data to better understand how new cancer therapies perform outside of clinical trials. By leveraging advancements in genomics and electronic health records, the project aims to identify which patient populations may benefit most from these therapies. The study will also explore patient-reported outcomes to assess the quality of life impacts of these treatments. Ultimately, the goal is to generate real-world evidence that can inform regulatory decision-making regarding cancer therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research include cancer patients who are receiving or considering new therapies and have diverse biological characteristics.

Not a fit: Patients with conditions unrelated to cancer or those not receiving new cancer therapies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments, improving patient outcomes and quality of life.

How similar studies have performed: Other research has shown promise in using real-world data to inform treatment decisions, indicating that this approach could be effective.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.