Understanding the roles of understudied proteins in diseases
Illuminating the Druggable Genome Data Coordinating Center - Engagement Plan with the CFDE
This study is working to gather and simplify information about certain proteins that are not well understood, especially those linked to important health issues, so that everyone can learn more about how these proteins might affect diseases and help patients understand their genetic health better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10217890 on NIH RePORTER |
What this research studies
This research aims to consolidate and harmonize various protein and disease-related data from multiple sources, making it accessible to the public. It focuses on understudied proteins, particularly those in the G-protein coupled receptor, ion channel, and protein kinase families, to uncover their functions and potential roles in specific diseases. By developing automated workflows and a comprehensive protein knowledgebase, the project seeks to enhance our understanding of the 'dark genome' and its implications for health. Patients may benefit from improved insights into genetic factors that influence their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic mutations or disorders related to the proteins being studied.
Not a fit: Patients with conditions unrelated to the proteins or pathways being investigated may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better-targeted therapies and personalized treatment options for patients with genetic disorders.
How similar studies have performed: Other research initiatives focusing on the druggable genome have shown promise in identifying new therapeutic targets, indicating that this approach has potential for success.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Lambert, Christophe G. — University of New Mexico Health Scis Ctr
- Study coordinator: Lambert, Christophe G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.