Understanding the roles of specific proteins in cellular stress responses
Signaling, Sensing, and Enzymatic Roles of Disordered Selenoproteins
['FUNDING_OTHER'] · UNIVERSITY OF DELAWARE · NIH-10842544
This study is looking at two proteins that help our cells handle stress, and it aims to understand how they might be connected to diseases like diabetes, cancer, and heart problems, which could lead to better ways to manage these conditions for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF DELAWARE (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-10842544 on ClinicalTrials.gov |
What this research studies
This research investigates the functions of two proteins, selenoprotein K and selenoprotein S, which are involved in how cells respond to stress. The study aims to explore how these proteins contribute to various cellular processes, including protein quality control and gene expression. By examining their interactions and roles within the cell, the research seeks to uncover their potential links to diseases such as diabetes, cancer, and cardiovascular conditions. Patients may benefit from insights gained about these proteins and their implications for disease management.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for or diagnosed with adult-onset diabetes, cardiovascular diseases, or certain cancers.
Not a fit: Patients with conditions unrelated to cellular stress responses or those not at risk for the studied diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating diseases like diabetes and cancer.
How similar studies have performed: Previous research has shown promising results in understanding the roles of selenoproteins in cellular processes, suggesting potential for success in this area.
Where this research is happening
Newark, UNITED STATES
- UNIVERSITY OF DELAWARE — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROZOVSKY, SHARON — UNIVERSITY OF DELAWARE
- Study coordinator: ROZOVSKY, SHARON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus, Cancer Prognosis, Cancers, Cardiovascular Diseases