Understanding the role of viruses in oral health

Integrated computational approaches to determine contributions of the oral virome

NIH-funded research University of Iowa · NIH-10948143

This study is looking at how viruses in your mouth interact with other tiny organisms and how they might affect your oral health, which could help improve prevention and treatment for conditions like Burkitt lymphoma and other oral diseases.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-10948143 on NIH RePORTER

What this research studies

This research investigates the complex interactions between viruses and other microorganisms in the oral cavity, focusing on how these viral communities, known as the oral virome, influence oral health and disease. By utilizing advanced sequencing technologies, the study aims to uncover the contributions of various viruses to the oral microbiome and their potential effects on health outcomes. Patients may benefit from insights gained about the virome's role in conditions like Burkitt lymphoma and other oral diseases, leading to improved prevention and treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with oral health issues or those at risk for conditions influenced by the oral virome.

Not a fit: Patients with no oral health concerns or those not affected by viral influences in the oral cavity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing and treating oral diseases by understanding the role of viruses in oral health.

How similar studies have performed: While research on the oral virome is relatively new, preliminary studies have shown promising results, indicating that this area of investigation could yield significant insights.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.