Understanding the role of the tumor environment in pancreatic cancer

PASSCODE (Pancreatic Adenocarcinoma Stromal Reprograming ConSortium COordination, Data Management and Education)

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-10915479

This study is looking at how certain supportive cells in the environment around pancreatic cancer tumors affect the growth of the disease, with the hope that this research will lead to better treatments for patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10915479 on NIH RePORTER

What this research studies

This research focuses on pancreatic ductal adenocarcinoma (PDAC) and its unique tumor environment, which includes various supportive cells and structures. The project aims to investigate how these stromal components, particularly cancer-associated fibroblasts, influence the development and progression of pancreatic cancer. By coordinating efforts among multiple research sites, the initiative seeks to enhance collaboration and data sharing, ultimately leading to better insights into the disease. Patients may benefit from improved understanding and potential new treatment strategies derived from this research.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic ductal adenocarcinoma.

Not a fit: Patients with other types of cancer or those without a diagnosis of pancreatic ductal adenocarcinoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic approaches that target the tumor microenvironment in pancreatic cancer.

How similar studies have performed: Previous research has shown promising results in understanding the tumor microenvironment in other cancers, suggesting potential for success in this novel approach.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions American Cancer SocietyCancer Biology
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.