Understanding the role of Superoxide Dismutase I in Parkinson's Disease
Investigation of Superoxide Dismutase I in Parkinson's Disease
This study is looking at how a protein called SOD1 interacts with another protein linked to Parkinson's Disease, and it aims to understand how these interactions might affect the progression of the disease, with the help of patients who can provide samples or share their experiences.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mc Laughlin Research Institute NIH-funded |
| Lab location | 1 site (Great Falls, United States) |
| Project ID | NIH-11004637 on NIH RePORTER |
What this research studies
This research investigates how Superoxide Dismutase 1 (SOD1) interacts with alpha synuclein in Parkinson's Disease (PD). By examining brain tissue from PD patients, the study aims to uncover the relationship between SOD1 aggregates and the progression of the disease. The approach includes analyzing genetic factors and protein interactions that may contribute to neurodegeneration. Patients may be involved in providing biological samples or participating in assessments related to their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's Disease, particularly those with genetic factors related to alpha synuclein.
Not a fit: Patients with Parkinson's Disease who do not have any genetic mutations or variants related to alpha synuclein may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the mechanisms of Parkinson's Disease and potential therapeutic targets.
How similar studies have performed: Previous research has shown that investigating protein interactions in neurodegenerative diseases can yield significant insights, suggesting this approach may be promising.
Where this research is happening
Great Falls, United States
- Mc Laughlin Research Institute — Great Falls, United States (Active)
Researchers
- Principal investigator: Leavens, Moses — Mc Laughlin Research Institute
- Study coordinator: Leavens, Moses
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.