Understanding the risks of acute respiratory failure in patients with hospital-onset sepsis
Treatment implications of heterogeneity in acute respiratory failure risk among patients with hospital-onset sepsis
This study looks at how patients with hospital-onset sepsis might face different chances of developing breathing problems, and it aims to find better ways to treat those at higher risk so they can get the care they need to feel better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11082526 on NIH RePORTER |
What this research studies
This research investigates how different patients with hospital-onset sepsis (HOS) experience varying risks of developing acute respiratory failure (ARF). By analyzing data from multiple hospitals, the study aims to identify specific characteristics and treatment responses among these patients. The goal is to develop tailored treatment strategies that improve outcomes by addressing the unique needs of individuals at high risk for ARF. This approach seeks to enhance the timing and effectiveness of interventions for vulnerable patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with hospital-onset sepsis who are at risk of developing acute respiratory failure.
Not a fit: Patients with community-onset sepsis or those not experiencing hospital-onset sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols that significantly reduce the risk of acute respiratory failure in patients with hospital-onset sepsis.
How similar studies have performed: Preliminary studies have shown promising associations between treatment timing and outcomes in similar patient populations, indicating potential for success in this research.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Ginestra, Jennifer Claire — University of Colorado Denver
- Study coordinator: Ginestra, Jennifer Claire
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.