Understanding the real-world benefits and risks of lung cancer screening
Applying causal inference methods to improve estimation of the real-world benefits and harms of lung cancer screening
This project helps us understand how well lung cancer screening works for everyday people, not just those in clinical trials.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11095973 on NIH RePORTER |
What this research studies
Clinical trials show that lung cancer screening can save lives, but it also has downsides like false alarms and follow-up procedures. We know that people who get screened in the real world are often different from those in trials, and many don't complete all recommended screenings. This project aims to use advanced methods to get a clearer picture of the actual benefits and harms of lung cancer screening for the general population. By looking at real-world data, we hope to make screening programs more effective and tailored to patients' needs.
Who could benefit from this research
Good fit: This research is relevant to individuals who are eligible for or considering lung cancer screening, especially those who might not fit the profile of typical clinical trial participants.
Not a fit: Patients who are not at risk for lung cancer or are not eligible for screening would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective and personalized lung cancer screening programs, helping more people benefit while minimizing risks.
How similar studies have performed: While clinical trials have shown the effectiveness of lung cancer screening, this project uses novel causal inference methods to specifically address the real-world effectiveness outside of controlled trial settings.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Lund, Jennifer — Univ of North Carolina Chapel Hill
- Study coordinator: Lund, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.