Understanding the proteins involved in Sézary Syndrome
Epiproteomics of Sezary Syndrome
This study is looking at how Sézary Syndrome, a serious skin cancer, develops by examining the proteins involved, with the goal of finding better ways to diagnose it and create more personalized treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10867311 on NIH RePORTER |
What this research studies
This research investigates the underlying mechanisms of Sézary Syndrome, a type of aggressive skin cancer, by analyzing the proteins involved in its development. The study aims to identify objective biomarkers that can improve diagnostic accuracy and help in the timely identification of patients with this condition. By focusing on the epiproteome, the research seeks to enhance the understanding of how this cancer progresses and responds to treatments. Patients may benefit from the development of targeted therapies that are more effective and personalized based on their specific disease characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Sézary Syndrome or those exhibiting symptoms of cutaneous T-cell lymphomas.
Not a fit: Patients with other types of cancers or those without a diagnosis of Sézary Syndrome may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted treatments for patients with Sézary Syndrome.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for other types of cancers, suggesting that this approach may yield valuable insights for Sézary Syndrome as well.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Elenitoba-Johnson, Kojo S. J. — Sloan-Kettering Inst Can Research
- Study coordinator: Elenitoba-Johnson, Kojo S. J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.