Understanding the patterns of opioid and stimulant use to prevent overdoses

The short and long-term dynamics of opioid/stimulant use: Mixed methods to informoverdose prevention and treatment related to polysubstance use

NIH-funded research Johns Hopkins University · NIH-10590209

This study is looking at how using opioids and stimulants together can affect the risk of overdose and treatment options, so we can find better ways to help people who might be at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10590209 on NIH RePORTER

What this research studies

This research investigates the complex dynamics of using opioids and stimulants together, focusing on how these patterns affect overdose risks and treatment options. By collecting data from community samples, the study aims to identify both short-term and long-term trends in polysubstance use. It will also explore how treatment for opioid use disorder interacts with stimulant use and its implications for overdose prevention. The findings will help inform better treatment strategies and prevention services for individuals at risk of overdose.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who use both opioids and stimulants and are at risk of overdose.

Not a fit: Patients who only use opioids or only use stimulants without concurrent use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and prevention strategies for individuals struggling with polysubstance use, ultimately reducing overdose deaths.

How similar studies have performed: Previous research has shown that understanding the dynamics of polysubstance use can lead to effective interventions, making this approach both relevant and necessary.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immunodeficiency SyndromeAcquired Immune Deficiency SyndromeAcquired Immuno-Deficiency SyndromeAcquired Immunologic Deficiency Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.