NIH-funded research Career grant

Understanding the oral microbiome development in Latinx children at the US-Mexico border

Official title: Oral microbiome establishment and development of Latinx Children at the US-Mexico border

Funded at University of California Los Angeles · NIH-10873955 · Data updated 2026-11-12

This study looks at how the mouth bacteria of Latinx children changes from birth to age three, especially for those born near the US-Mexico border, to help find ways to keep their teeth healthy and prevent cavities.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$139,185
NIH project number5K01DE032775-02
Project IDNIH-10873955 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Latinx children born along the US-Mexico border, particularly those under three years of age.

Less likely to help

Patients who are not Latinx or those outside the early childhood age range may not benefit from this research.

What this research studies

This research investigates how the oral microbiome of Latinx children develops during their early years, particularly from birth to three years old. By analyzing salivary samples collected at various stages, the study aims to identify changes in the microbiome that may influence oral health and the risk of dental caries. The research focuses on children born along the US-Mexico border, a population that faces unique health challenges. The findings could lead to personalized strategies for preventing oral diseases in young children.

Why it matters

Potential benefit: If successful, this research could lead to improved oral health outcomes and preventive strategies for children at risk of dental issues.

How similar studies have gone: Previous research has shown that understanding the microbiome can significantly impact health outcomes, suggesting this approach may yield valuable insights.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Wang, Yan — University of California Los Angeles
  • Study coordinator: Wang, Yan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.