Understanding the mouth's bacteria and inflammation in HIV
Role of the oral microbiome in driving local and systemic inflammation in HIV
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11145128
This research explores how the bacteria in your mouth might contribute to ongoing inflammation and other health issues for people living with HIV.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11145128 on ClinicalTrials.gov |
What this research studies
Even with successful treatment, many people with chronic HIV still experience inflammation and related health problems. We want to understand if the bacteria living in the mouth play a part in this ongoing inflammation and the accelerated development of other conditions. Our work will look at how these oral bacteria might move to the gut and affect the body's overall inflammatory response. By learning more about these connections, we hope to find new ways to improve the health of individuals with HIV.
Who could benefit from this research
Good fit: This research is relevant for patients living with chronic HIV who experience ongoing inflammation or related health issues.
Not a fit: Patients without HIV or those whose inflammation is not linked to the oral microbiome may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new strategies for reducing chronic inflammation and preventing related health complications in people with HIV.
How similar studies have performed: While the gut microbiome has been extensively studied, research specifically on the oral microbiome's role in HIV-related inflammation is limited, making this a novel area of focus.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FULCHER, JENNIFER — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: FULCHER, JENNIFER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus