Understanding the molecular features of progressive pulmonary sarcoidosis
Molecular Characterization of Progressive Pulmonary Sarcoidosis
['FUNDING_R01'] · NATIONAL JEWISH HEALTH · NIH-10912435
This study is looking at the unique proteins and genes in people with sarcoidosis to help find out who might be at risk for their lung condition getting worse, so we can create better ways to predict and manage the disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NATIONAL JEWISH HEALTH (nih funded) |
| Locations | 1 site (DENVER, UNITED STATES) |
| Trial ID | NIH-10912435 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular characteristics of progressive pulmonary sarcoidosis, a condition affecting the lungs in patients with sarcoidosis. By enrolling patients with sarcoidosis, the study aims to identify specific proteins and genes that could indicate a higher risk of disease progression. The research will utilize laboratory models and analyze blood samples to uncover biological pathways involved in the disease. The ultimate goal is to develop clinical tools for early prediction and management of progressive sarcoidosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with sarcoidosis, particularly those experiencing pulmonary symptoms.
Not a fit: Patients with sarcoidosis who do not have pulmonary involvement or those with non-progressive forms of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and treatment of patients at risk for severe lung complications from sarcoidosis.
How similar studies have performed: While there have been studies on sarcoidosis, this research aims to explore novel molecular pathways that have not been extensively investigated, making it a potentially groundbreaking approach.
Where this research is happening
DENVER, UNITED STATES
- NATIONAL JEWISH HEALTH — DENVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAIER, LISA A — NATIONAL JEWISH HEALTH
- Study coordinator: MAIER, LISA A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Besnier-Boeck Disease