Understanding the molecular factors that influence cardiorespiratory fitness
Integrative analysis of genomics and proteomics to identify candidate molecular transducers of cardiorespiratory fitness
This study is looking at how our genes and proteins influence our fitness levels and how we respond to exercise, so if you join, you could help us find ways to improve health and fitness for everyone!
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10990253 on NIH RePORTER |
What this research studies
This research investigates the biological factors that affect cardiorespiratory fitness (CRF), which is crucial for overall health and longevity. By analyzing genetic and protein data from participants, the study aims to identify specific molecules that play a role in how individuals respond to exercise training. The research utilizes advanced techniques, including whole genome sequencing and plasma proteomics, to gather comprehensive data on the body's response to exercise. Participants may contribute to a better understanding of how to enhance fitness and health outcomes through targeted interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are interested in understanding their fitness levels and how they can improve them through exercise.
Not a fit: Patients who are not interested in exercise or who have conditions that prevent them from participating in physical activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cardiorespiratory fitness, potentially reducing the risk of mortality and enhancing overall health.
How similar studies have performed: Previous research has shown promise in identifying molecular factors related to exercise and fitness, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Robbins, Jeremy — Beth Israel Deaconess Medical Center
- Study coordinator: Robbins, Jeremy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.