Understanding the molecular factors that influence cardiorespiratory fitness
Official title: Integrative analysis of genomics and proteomics to identify candidate molecular transducers of cardiorespiratory fitness
Funded at Beth Israel Deaconess Medical Center · NIH-10990253 · Data updated 2026-11-12
This study is looking at how our genes and proteins influence our fitness levels and how we respond to exercise, so if you join, you could help us find ways to improve health and fitness for everyone!
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 17, 2024 |
| Project end | September 16, 2025 |
| Funding year | 2024 |
| Award (this year) | $345,800 |
| NIH project number | 1R03OD038387-01 |
| Project ID | NIH-10990253 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are interested in understanding their fitness levels and how they can improve them through exercise.
✕Less likely to help
Patients who are not interested in exercise or who have conditions that prevent them from participating in physical activity may not benefit from this research.
What this research studies
This research investigates the biological factors that affect cardiorespiratory fitness (CRF), which is crucial for overall health and longevity. By analyzing genetic and protein data from participants, the study aims to identify specific molecules that play a role in how individuals respond to exercise training. The research utilizes advanced techniques, including whole genome sequencing and plasma proteomics, to gather comprehensive data on the body's response to exercise. Participants may contribute to a better understanding of how to enhance fitness and health outcomes through targeted interventions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cardiorespiratory fitness, potentially reducing the risk of mortality and enhancing overall health.
How similar studies have gone: Previous research has shown promise in identifying molecular factors related to exercise and fitness, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Robbins, Jeremy — Beth Israel Deaconess Medical Center
- Study coordinator: Robbins, Jeremy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.