Understanding the molecular causes of chronic pain
Human Nociceptor and Spinal Cord Molecular Signature Center
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS DALLAS · NIH-10930039
This study is looking at the tiny nerve cells in people with chronic pain to understand how pain signals work in the body, which could help find better ways to treat conditions like neuropathic pain, neck pain, and back pain.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS DALLAS (nih funded) |
| Locations | 1 site (RICHARDSON, UNITED STATES) |
| Trial ID | NIH-10930039 on ClinicalTrials.gov |
What this research studies
This research investigates the biological mechanisms behind chronic pain by analyzing human dorsal root ganglion tissues. The team uses advanced techniques to study individual sensory neurons from patients suffering from chronic pain conditions, such as neuropathic pain, chronic neck pain, and low back pain. By examining these neurons at a molecular level, the research aims to uncover how pain signals are activated and processed in the body. The findings could lead to new approaches for treating chronic pain based on a deeper understanding of the pain pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults suffering from chronic pain conditions, particularly those undergoing surgeries involving dorsal root ganglion or peripheral nerve removal.
Not a fit: Patients with acute pain or those not experiencing chronic pain conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for chronic pain, improving the quality of life for many patients.
How similar studies have performed: Previous research has shown promise in understanding pain mechanisms through similar molecular approaches, indicating potential for success in this area.
Where this research is happening
RICHARDSON, UNITED STATES
- UNIVERSITY OF TEXAS DALLAS — RICHARDSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PRICE, THEODORE J. — UNIVERSITY OF TEXAS DALLAS
- Study coordinator: PRICE, THEODORE J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Center