NIH-funded research NIH-funded research

Understanding the microbiome in chronic wounds from lymphatic filariasis in Ghana.

Official title: Microbiome profiling of non-healing filarial lymphedema wounds in Ghana.

Funded at Kwame Nkrumah University/science/tech · NIH-10979516 · Data updated 2026-11-12

This study is looking at the germs in stubborn wounds caused by lymphatic filariasis in Ghana to find out what makes them different and how they resist treatment, with the goal of helping doctors improve care for patients dealing with these tough wounds.

More Lymphedema research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionKwame Nkrumah University/science/tech
NIH-funded
Lab location1 site (Kumasi, Ghana)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$89,534
NIH project number1K43TW012795-01
Project IDNIH-10979516 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals suffering from chronic non-healing wounds due to lymphatic filariasis in Ghana.

Less likely to help

Patients with wounds not related to lymphatic filariasis or those outside of Ghana may not benefit from this research.

What this research studies

This research focuses on the microbiome profiles of non-healing wounds caused by lymphatic filariasis in Ghana. It aims to identify unique microbial signatures and resistance patterns in these wounds using advanced technologies like the QIIME 2 platform. By understanding the bacterial and fungal communities present, the research seeks to improve treatment approaches and healthcare outcomes for patients suffering from this condition. The project will also develop a genomic library specific to lymphatic filariasis and predictive algorithms to monitor wound healing.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for chronic wounds in patients with lymphatic filariasis, improving their quality of life.

How similar studies have gone: While the specific approach of profiling the microbiome in lymphedema wounds is novel, similar studies have shown promise in understanding microbial influences on wound healing.

Where this research is happening

  • Kwame Nkrumah University/science/tech
    Kumasi, Ghana
    Active

Researchers

  • Principal investigator: Kwarteng, Alexander — Kwame Nkrumah University/science/tech
  • Study coordinator: Kwarteng, Alexander

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.