Understanding the mechanics behind Achilles tendon pain

Defining neuromechanical mechanisms of Achilles tendinopathy

NIH-funded research University of Pennsylvania · NIH-10897990

This study is looking at how different movements and muscle activities affect healing and pain in people with Achilles tendinopathy, so we can find better ways to help you recover and feel better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10897990 on NIH RePORTER

What this research studies

This research investigates the underlying neuromechanical factors contributing to Achilles tendinopathy, a painful condition affecting the tendon. By using advanced techniques like High-Density surface ElectroMyoGraphy (HDsEMG), the study aims to analyze how different movements and muscle contributions impact tendon healing and pain levels. Patients will undergo specific tests to assess their tendon loading and biomechanics during various activities, helping to identify personalized rehabilitation strategies. The goal is to improve treatment outcomes for individuals suffering from this chronic condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic pain from mid-substance Achilles tendinopathy.

Not a fit: Patients with acute Achilles injuries or those who do not have a diagnosis of Achilles tendinopathy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, tailored rehabilitation protocols for patients with Achilles tendinopathy.

How similar studies have performed: Previous research has shown promise in using biomechanical assessments to improve treatment outcomes for tendon injuries, indicating that this approach could be beneficial.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.