NIH-funded research R01 grant

Understanding the long-term effects of treatment in Hodgkin lymphoma patients

Official title: Modeling Multi-Source Data in Hodgkin Lymphoma

Funded at Tufts Medical Center · NIH-11046511 · Data updated 2026-11-12

This study is looking at how treatments for Hodgkin lymphoma might affect your health in the long run, especially regarding risks for other cancers and heart problems, using information from over 12,000 patients to help understand these effects better.

More Lymphoma research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTufts Medical Center
NIH-funded
Lab location1 site (Boston, United States)
Project startMarch 1, 2022
Project endFebruary 28, 2027
Funding year2025
Award (this year)$600,045
NIH project number5R01CA262265-04
Project IDNIH-11046511 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 21 and older who have been treated for Hodgkin lymphoma and are currently undergoing active follow-up care.

Less likely to help

Patients who have not received treatment for Hodgkin lymphoma or those who are not in the active follow-up phase may not benefit from this research.

What this research studies

This research investigates the long-term health impacts of Hodgkin lymphoma treatments, focusing on late effects such as secondary cancers and cardiovascular diseases. By utilizing data from over 12,000 patients across multiple clinical trials and registries, the study aims to create a comprehensive model that links treatment outcomes with patient health over time. The approach involves collaboration among experts in oncology, epidemiology, and data science to analyze and harmonize patient data for better insights into post-treatment morbidity and survival.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that minimize long-term health risks for Hodgkin lymphoma survivors.

How similar studies have gone: Previous research has successfully utilized similar data modeling approaches to understand long-term outcomes in cancer patients, indicating a promising potential for this study.

Where this research is happening

  • Tufts Medical Center
    Boston, United States
    Active

Researchers

  • Principal investigator: Parsons, Susan Kenyon — Tufts Medical Center
  • Study coordinator: Parsons, Susan Kenyon

Related research

Other NIH-funded projects on the same topics.

  • Understanding why Black and Hispanic Hodgkin lymphoma patients have worse survival

    A patient-centered study to uncover social and care factors that contribute to lower survival among Black and Hispanic people with Hodgkin lymphoma across all ages.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11572148

  • Novel combination therapy for non-Hodgkin lymphoma in people and dogs

    A new treatment combo using an oncolytic virus and other therapies is being tested to help people with hard-to-treat non-Hodgkin lymphoma, with studies also involving dogs to better understand responses.

    NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11473229

  • Trajectories of Neurotoxicity in young Hodgkin lymphoma patients

    Aging Hodgkin lymphoma patients who are adolescents or young adults may face long-lasting brain and nerve-related side effects from their cancer treatment, and this study aims to map how those problems develop over time.

    NIH research University of Rochester · Rochester, United States · NIH-11432883

  • Combination therapy approach for non-Hodgkin lymphoma (NHL)

    A Mayo Clinic team is testing a new combination treatment for non-Hodgkin lymphoma to improve responses in patients and in dogs with similar disease.

    NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11402652

  • Multi-antigen T cell therapy for relapsed NHL

    A patient-derived T cell therapy called MT-601 targets six tumor-associated antigens to help treat relapsed non-Hodgkin lymphoma after other therapies may have failed.

    NIH research Marker Therapeutics, INC. · Houston, United States · NIH-11374461

  • Personalized de‑intensification of therapy for NLP Hodgkin lymphoma

    A clinician-scientist at Stanford is developing a patient-centered program to tailor and reduce therapy for nodular lymphocyte-predominant Hodgkin lymphoma using tumor and blood samples.

    NIH research Stanford University · Stanford, United States · NIH-11355615

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.