Understanding the long-term effects of radiation treatment in head and neck cancer survivors

Who could benefit from this research

What this research studies

This research investigates the long-term effects of radiation-induced fibrosis and other treatment-related complications in survivors of head and neck cancer. It aims to identify the patterns of these adverse effects over time and explore potential biological markers that could predict who is at risk for developing severe complications. By analyzing the experiences of cancer survivors, the study seeks to develop tailored interventions that can improve their quality of life and reduce debilitating symptoms like neck disability and difficulty swallowing.

Why it matters

Where this research is happening

• University of Pittsburgh at Pittsburgh
  Pittsburgh, United States Active

Researchers

• Principal investigator: Nilsen, Marci Lee — University of Pittsburgh at Pittsburgh
• Study coordinator: Nilsen, Marci Lee

Related research

Other NIH-funded projects on the same topics.

• Radiation-related scarring and related effects in head and neck cancer survivors

  A study looking at how fibrosis from radiation affects neck movement, swallowing, and daily life in people who have survived head and neck cancer.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11377529

• Understanding and Managing Treatment Side Effects for Head and Neck Cancer Survivors

  This research aims to better understand how radiation treatment for head and neck cancer leads to long-term side effects like neck stiffness and difficulty swallowing, and to find ways to help survivors feel better.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11132582

• Biological and social factors shaping psychosocial outcomes in advanced head and neck cancer patients on immunotherapy

  This grant studies how biology and social factors influence mental and emotional well-being in people with advanced head and neck cancer who are receiving immunotherapy.

  NIH research Emory University · Atlanta, United States · NIH-11362490

• Photobiomodulation therapy for chronic head and neck lymphedema in cancer survivors

  A 5-year, multi-site trial tests a light-based therapy to reduce long-term neck and jaw swelling in people who survived head and neck cancer.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11324201

• Tele-CBT program to reduce body image distress after head and neck cancer

  This project offers a five-session remote cognitive behavioral therapy (BRIGHT) to help head and neck cancer survivors who are struggling with appearance, speech, or swallowing changes.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11237982

• Understanding emotional and social challenges for people with advanced head and neck cancer on immunotherapy

  This project aims to understand the emotional and social challenges faced by patients with advanced head and neck cancer who are receiving immunotherapy.

  NIH research Emory University · Atlanta, United States · NIH-11177880

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.