Understanding the long-term effects of radiation exposure in nonhuman primates
The Wake Forest Nonhuman Primate Radiation Survivor Cohort
This study looks at how radiation exposure affects the long-term health of rhesus monkeys, helping us understand potential health problems like organ issues and metabolic diseases that could also be relevant for people.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-11112981 on NIH RePORTER |
What this research studies
This research investigates the delayed effects of radiation exposure on nonhuman primates, focusing on how such exposure can lead to long-term health issues like organ dysfunction and metabolic diseases. The study involves a cohort of rhesus monkeys that have been observed for up to 15 years after receiving various doses of radiation. Researchers conduct annual clinical examinations, imaging studies, and pathology assessments to gather data on the health outcomes of these animals, including the impact of potential mitigating treatments.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals exposed to radiation, particularly those with a history of acute radiation exposure.
Not a fit: Patients who have not been exposed to radiation or do not have related health concerns may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide valuable insights into the long-term health effects of radiation exposure, potentially leading to improved treatments and preventive measures for affected individuals.
How similar studies have performed: Previous research has shown success in understanding the effects of radiation exposure in animal models, making this approach a continuation of established methodologies.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Cline, J. Mark — Wake Forest University Health Sciences
- Study coordinator: Cline, J. Mark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.