Understanding the long-term effects of COVID-19
Official title: OTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository Core
Funded at New York University School of Medicine · NIH-11301210 · Data updated 2026-11-12
This study is looking at the long-term health effects that people who have recovered from COVID-19 might experience, and it's for anyone who has had the virus and wants to help researchers understand lingering symptoms better by sharing their health information and samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 24, 2021 |
| Project end | May 23, 2025 |
| Funding year | 2025 |
| Award (this year) | $90,000 |
| NIH project number | 3OT2HL161847-01S4 |
| Project ID | NIH-11301210 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recovered from COVID-19 and are experiencing ongoing health problems.
✕Less likely to help
Patients who have not had COVID-19 or those who are not experiencing any post-acute symptoms may not benefit from this research.
What this research studies
This research investigates the long-term health effects experienced by individuals who have recovered from COVID-19. It aims to collect and analyze data from patients to better understand the post-acute sequelae of SARS-CoV-2 infection, which may include a range of physical and mental health issues. Patients may be asked to participate by providing health information and biological samples to help build a comprehensive biorepository. The goal is to identify patterns and potential treatments for those suffering from lingering symptoms.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of long-term COVID-19 symptoms, benefiting many patients who experience these issues.
How similar studies have gone: Other research has shown success in understanding post-viral syndromes, suggesting that this approach could yield valuable insights into the long-term effects of COVID-19.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Katz, Stuart D — New York University School of Medicine
- Study coordinator: Katz, Stuart D
Related research
Other NIH-funded projects on the same topics.
-
How COVID-19 infection and genes may influence memory and dementia risk
This study looks at how getting COVID-19 and a person’s genes together affect the chance of developing memory problems and Alzheimer’s disease later in life.
-
Alzheimer’s-related dementia after COVID-19: how SARS-CoV-2 affects the brain and potential drug repurposing
This research looks at how COVID-19 may contribute to dementia by studying brain inflammation, blood vessel injury, and virus-host interactions, with the goal of finding existing drugs that could help.
-
IL-22’s role in SARS-CoV-2 infection and tissue protection
A short study to understand how the cytokine IL-22 might help protect tissues during and after COVID-19 infection, especially in people with complications related to acute graft-versus-host disease.
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Maternal SARS-CoV-2 infection and its effects on placenta and child development
This grant studies how COVID-19 infection during pregnancy might change the placenta and influence a child’s brain development, especially in kids who may be at higher genetic risk for ADHD/ASD.
-
How COVID-19 and genetics influence memory and dementia risk in older adults
This project studies how getting COVID-19 interacts with people’s genetic makeup to affect the likelihood of cognitive decline and Alzheimer’s disease in older adults from diverse backgrounds.
-
Impact of COVID-19 on latent TB reactivation in Kenya
This project in Kenya checks how having had COVID-19 might influence the reactivation of latent tuberculosis in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.