Understanding the long-term effects of congenital Zika syndrome in children
Official title: Clinical progression and predictors of outcomes in congenital Zika syndrome
Funded at Research Triangle Institute · NIH-11146404 · Data updated 2026-11-12
This study is looking at how children with congenital Zika syndrome grow and develop over time, following a group of 187 kids from birth into their middle childhood to understand their health needs better and help their families.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project start | August 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $636,148 |
| NIH project number | 5R01HD112407-02 |
| Project ID | NIH-11146404 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children diagnosed with congenital Zika syndrome who have been followed since birth.
✕Less likely to help
Patients who do not have congenital Zika syndrome or those who are not part of the longitudinal cohort may not benefit from this research.
What this research studies
This research investigates the long-term health and developmental outcomes of children affected by congenital Zika syndrome (CZS). By following a cohort of 187 children from birth into middle childhood, the study aims to identify the evolution of clinical signs and assess various health outcomes using advanced imaging and monitoring techniques. The research will also explore factors that may influence these outcomes, providing valuable insights into the needs of children with CZS and their families.
Why it matters
Potential benefit: If successful, this research could lead to improved care strategies and support for children with congenital Zika syndrome.
How similar studies have gone: Previous research has shown success in longitudinal studies of congenital conditions, indicating that this approach is promising for understanding CZS.
Where this research is happening
-
Research Triangle Institute
Research Triangle Park, United States Active
Researchers
- Principal investigator: Wheeler, Anne Caroline — Research Triangle Institute
- Study coordinator: Wheeler, Anne Caroline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.