Understanding the long-term effects of congenital Zika syndrome in children

Clinical progression and predictors of outcomes in congenital Zika syndrome

NIH-funded research Research Triangle Institute · NIH-11146404

This study is looking at how children with congenital Zika syndrome grow and develop over time, following a group of 187 kids from birth into their middle childhood to understand their health needs better and help their families.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11146404 on NIH RePORTER

What this research studies

This research investigates the long-term health and developmental outcomes of children affected by congenital Zika syndrome (CZS). By following a cohort of 187 children from birth into middle childhood, the study aims to identify the evolution of clinical signs and assess various health outcomes using advanced imaging and monitoring techniques. The research will also explore factors that may influence these outcomes, providing valuable insights into the needs of children with CZS and their families.

Who could benefit from this research

Good fit: Ideal candidates for this research are children diagnosed with congenital Zika syndrome who have been followed since birth.

Not a fit: Patients who do not have congenital Zika syndrome or those who are not part of the longitudinal cohort may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved care strategies and support for children with congenital Zika syndrome.

How similar studies have performed: Previous research has shown success in longitudinal studies of congenital conditions, indicating that this approach is promising for understanding CZS.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.