Understanding the long-term effects of breathing issues in preterm infants
Official title: Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Funded at Lurie Children's Hospital of Chicago · NIH-11004618 · Data updated 2026-11-12
This study is looking at how short episodes of low oxygen levels in preterm babies might impact their health as they grow up, especially concerning breathing problems like asthma and sleep issues, so we can find ways to help those babies early on for a healthier future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | December 15, 2021 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,428,980 |
| NIH project number | 5R01HL157256-04 |
| Project ID | NIH-11004618 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are preterm infants who have experienced intermittent hypoxemia during their neonatal care.
✕Less likely to help
Patients who were not born preterm or did not experience intermittent hypoxemia during their neonatal period may not benefit from this research.
What this research studies
This research investigates how intermittent hypoxemia, a condition where preterm infants experience brief periods of low oxygen levels, affects their health as they grow. By combining detailed clinical assessments with advanced data analysis, the study aims to create personalized models that predict long-term outcomes for these infants, particularly focusing on respiratory issues like asthma and sleep disorders. The goal is to identify at-risk infants early, allowing for targeted interventions that could improve their health and quality of life as they reach preschool age.
Why it matters
Potential benefit: If successful, this research could lead to better identification and management of respiratory issues in preterm infants, ultimately improving their long-term health outcomes.
How similar studies have gone: Other research has shown promising results in understanding the long-term effects of neonatal conditions on respiratory health, making this approach both relevant and potentially impactful.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Weese-Mayer, Debra Ellyn — Lurie Children's Hospital of Chicago
- Study coordinator: Weese-Mayer, Debra Ellyn
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.