Understanding the links between heart, kidney, and metabolic diseases
Official title: Cardiorenal and Metabolic Diseases Research Center
Funded at University of Mississippi Med Ctr · NIH-11033656 · Data updated 2026-11-12
This study is looking at how obesity and diabetes can lead to heart and kidney problems, especially for people in Mississippi, and it aims to find new ways to help improve health for those dealing with these issues.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Mississippi Med Ctr NIH-funded |
| Lab location | 1 site (Jackson, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $250,000 |
| NIH project number | 3P30GM149404-02S1 |
| Project ID | NIH-11033656 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with cardiovascular, renal, or metabolic disorders, particularly those living in Mississippi.
✕Less likely to help
Patients without any of the targeted conditions or those who do not reside in the geographic area of focus may not benefit from this research.
What this research studies
This research focuses on the interconnectedness of cardiovascular, renal, and metabolic diseases, which are major health issues in the U.S., particularly in Mississippi. It aims to explore how conditions like obesity and diabetes contribute to heart and kidney problems. By bringing together a team of scientists from various fields, the project seeks to develop new treatment strategies and improve patient outcomes. The research will involve both basic science and clinical approaches to better understand these complex relationships.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for patients suffering from heart, kidney, and metabolic diseases.
How similar studies have gone: Previous research has shown promising results in understanding the relationships between these diseases, indicating that this approach has potential for significant advancements.
Where this research is happening
-
University of Mississippi Med Ctr
Jackson, United States Active
Researchers
- Principal investigator: Hall, John E — University of Mississippi Med Ctr
- Study coordinator: Hall, John E
Related research
Other NIH-funded projects on the same topics.
-
Postnatal and Prenatal Base Editing Therapies for Metabolic Diseases
This grant aims to advance genetic medicine that could one day treat metabolic diseases before or after birth using precise genome editing techniques.
-
Postnatal and Prenatal Base Editing for Metabolic Diseases
A large NIH grant is funding research to develop gene-editing methods that could treat metabolic diseases before and after birth.
-
GLP-1 producing engineered probiotics to help manage metabolic diseases
A research project aims to create probiotic bacteria that constantly deliver GLP-1 to help people with type 2 diabetes and obesity manage their condition.
-
Changing bile acids to help diabetes, fatty liver, and weight problems
This project is developing medicines that shift bile acid balance in the liver to help adults with type 2 diabetes, fatty liver disease, or obesity.
-
Precise gene editing before or after birth for metabolic diseases
This project develops precise gene-editing treatments given before birth or soon after to correct genetic metabolic conditions in children.
-
How a specific bacterium affects fat and metabolism
This study is looking at a new type of bacteria called Clostridium immunis to see how it might help manage body fat and improve conditions like type 2 diabetes, which could lead to new treatment options for people dealing with these metabolic issues.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.