Understanding the link between asthma and COPD using advanced data analysis
Official title: Integrative network-based analysis of multi-omics data to elucidate the molecular connection between asthma and COPD
Funded at Brigham and Women's Hospital · NIH-10870139 · Data updated 2026-11-12
This study is looking at how asthma and COPD are related, especially how things like being exposed to smoke before birth can affect lung health throughout life, and it's for anyone interested in understanding the biological factors that might influence these breathing conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 18, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $189,000 |
| NIH project number | 5K25HL150336-05 |
| Project ID | NIH-10870139 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a history of asthma, particularly those who may be at risk for developing COPD.
✕Less likely to help
Patients with unrelated respiratory conditions or those who do not have asthma or COPD may not benefit from this research.
What this research studies
This research investigates the connection between asthma and chronic obstructive pulmonary disease (COPD) by analyzing complex biological data from patients. It focuses on how factors like in utero smoke exposure may influence lung health from prenatal development through adulthood. By utilizing advanced network biology methods, the study aims to integrate various types of biological data to uncover the molecular mechanisms that contribute to these respiratory conditions. Patients' genetic and epigenetic information will be analyzed to better understand their disease trajectories.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for asthma and COPD, potentially reducing the burden of these diseases.
How similar studies have gone: Previous research has shown promise in using multi-omics approaches to understand complex diseases, suggesting that this methodology could yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Halu, Arda — Brigham and Women's Hospital
- Study coordinator: Halu, Arda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.