Understanding the internal clocks of malaria parasites
Defining and Exploiting the Circadian Clocks in Malaria Parasites
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-10687634
This study is looking at how malaria parasites have their own internal clocks that affect the fevers you experience when you're sick, and by understanding this better, we hope to find new ways to treat malaria.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA BERKELEY (nih funded) |
| Locations | 1 site (BERKELEY, UNITED STATES) |
| Trial ID | NIH-10687634 on ClinicalTrials.gov |
What this research studies
This research investigates the circadian rhythms of malaria parasites and how these rhythms contribute to the disease's characteristic fevers. By exploring the intrinsic clocks of the parasites, the study aims to uncover the molecular mechanisms that drive their replication and the resulting symptoms in infected individuals. The approach involves examining how these rhythms operate independently of the host's circadian system, potentially leading to new insights into malaria pathogenesis. Patients may benefit from a deeper understanding of how malaria operates, which could inform future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with malaria or those at high risk of malaria infection.
Not a fit: Patients with non-parasitic infections or those who do not have malaria will likely not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that target the malaria parasite's internal clock, improving treatment outcomes for patients.
How similar studies have performed: Other research has shown promise in understanding circadian rhythms in various pathogens, suggesting that this approach could yield valuable insights into malaria as well.
Where this research is happening
BERKELEY, UNITED STATES
- UNIVERSITY OF CALIFORNIA BERKELEY — BERKELEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RIJO-FERREIRA, FILIPA — UNIVERSITY OF CALIFORNIA BERKELEY
- Study coordinator: RIJO-FERREIRA, FILIPA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases, Infectious Disease Pathway, Infectious Diseases, Infectious Disorder