Understanding the impact of white matter lesions on cognitive health
Statistics Core
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10929344
This study is looking at small brain changes seen in MRI scans of people who have memory or thinking problems, and it aims to create better ways to collect and share this information to help us understand how these changes might affect cognitive decline.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10929344 on ClinicalTrials.gov |
What this research studies
This research focuses on the significance of incidental white matter lesions observed in MRI scans among diverse populations experiencing cognitive complaints. It aims to develop innovative tools for data collection and management, harmonize neuroimaging data across various clinical sites, and utilize advanced deep learning techniques to quantify white matter injury. The project will also perform statistical analyses to support investigators and share findings through a dedicated research portal. By integrating and analyzing this data, the research seeks to enhance our understanding of cognitive decline and its associated risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals from diverse backgrounds who have experienced cognitive complaints and have undergone MRI scans showing white matter lesions.
Not a fit: Patients without cognitive complaints or those who do not have MRI scans indicating white matter lesions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and risk assessments for cognitive decline and dementia.
How similar studies have performed: Previous research has shown promise in utilizing advanced imaging techniques and data harmonization to better understand cognitive impairments, indicating that this approach has potential for success.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAJAN, KUMAR B. — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: RAJAN, KUMAR B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.