Understanding the impact of HIV on COVID-19 severity
Curating a Knowledge Base for Individuals with Coinfection of HIV and SARS-CoV-2: EHR-based Data Mining
This study is looking at how having HIV might make COVID-19 worse for people who have both infections, and it aims to find out what factors could lead to more severe illness, so we can better care for those patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Carolina at Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project ID | NIH-10665078 on NIH RePORTER |
What this research studies
This research investigates how HIV infection affects the severity of COVID-19 in individuals who are coinfected with both viruses. By analyzing electronic health records (EHR) from a large cohort of patients, the study aims to identify risk factors and clinical characteristics that contribute to severe COVID-19 outcomes in those with HIV. The research will also explore the role of comorbidities and antiretroviral therapy in these patients. Ultimately, the goal is to enhance our understanding of the interactions between HIV and SARS-CoV-2 to improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are coinfected with HIV and SARS-CoV-2, particularly those with varying levels of CD4+ T-cell counts and viral loads.
Not a fit: Patients who are not coinfected with both HIV and SARS-CoV-2 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies and treatment protocols for patients with HIV who contract COVID-19.
How similar studies have performed: Previous research has indicated that understanding the interactions between HIV and other viral infections can lead to significant advancements in treatment, suggesting that this approach has potential for success.
Where this research is happening
Columbia, United States
- University of South Carolina at Columbia — Columbia, United States (Active)
Researchers
- Principal investigator: Li, Xiaoming — University of South Carolina at Columbia
- Study coordinator: Li, Xiaoming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.