Understanding the immune system's role in Parkinson's disease
Innate and Adaptive Immunity in Parkinson Disease
This study is looking at how the immune system works in people with Parkinson's disease to find ways to protect the brain and slow down the disease's progression.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10469383 on NIH RePORTER |
What this research studies
This research investigates how the immune system is activated in patients with Parkinson's disease (PD) and aims to develop strategies to protect the brain from neurodegeneration. Researchers will analyze immune responses in early stages of PD by examining brain tissue and exploring the effects of inhibiting specific signaling pathways. By identifying immune changes associated with PD, the study seeks to uncover potential therapeutic targets that could slow or stop the progression of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with early-stage Parkinson's disease who are experiencing immune system-related symptoms.
Not a fit: Patients with advanced Parkinson's disease or those without a diagnosis of Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly slow down or halt the progression of Parkinson's disease.
How similar studies have performed: Previous research has shown promise in targeting immune responses in neurodegenerative diseases, suggesting that this approach could yield significant advancements.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Standaert, David G. — University of Alabama at Birmingham
- Study coordinator: Standaert, David G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.