Understanding the immune response and predictive features of MIS-C in children
Immunologic and Predictive Features of MIS-C
This study is looking at how to better understand and manage multisystem inflammatory syndrome in children (MIS-C) that can happen after COVID-19, by comparing kids with MIS-C to healthy kids to find clues in their genes and immune systems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10866496 on NIH RePORTER |
What this research studies
This research investigates multisystem inflammatory syndrome in children (MIS-C), a condition that can occur after COVID-19 infection. The study will analyze clinical, genetic, and immunologic data from children diagnosed with MIS-C, comparing them to healthy controls. Using advanced technologies and machine learning algorithms, the researchers aim to identify specific immune and genetic markers that can help predict, diagnose, and manage MIS-C. This comprehensive approach seeks to enhance our understanding of the disease and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 who have been diagnosed with MIS-C or have had a recent COVID-19 infection.
Not a fit: Patients who are older than 11 years or those who have not been infected with COVID-19 are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for children affected by MIS-C.
How similar studies have performed: Other research has shown promise in understanding immune responses to COVID-19, making this approach both relevant and potentially impactful.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Bogunovic, Dusan — Columbia University Health Sciences
- Study coordinator: Bogunovic, Dusan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.