Understanding the immune environment in endometriosis
Endometrial immune microenvironment dysfunction in endometriosis pathobiology
This study is looking at how certain immune cells in the uterus might play a role in endometriosis, with the goal of finding new, easy ways to detect the condition earlier by checking menstrual blood for specific markers.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10950247 on NIH RePORTER |
What this research studies
This research investigates how the immune microenvironment in the uterus may contribute to endometriosis, a condition affecting many women. It aims to identify specific immune cells, particularly uterine natural killer (uNK) cells, and their role in the disease's development. By analyzing menstrual blood for biomarkers, the study seeks to develop non-invasive diagnostic tools that could lead to earlier detection of endometriosis. The research employs advanced techniques such as single-cell profiling and machine learning to analyze immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are women of reproductive age who experience symptoms suggestive of endometriosis.
Not a fit: Patients who do not have endometriosis or are beyond reproductive age may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of endometriosis, improving quality of life for affected women.
How similar studies have performed: Previous research has shown promise in understanding immune responses in endometriosis, but this approach focusing on uNK cells and menstrual blood biomarkers is relatively novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Feyaerts, Dorien — Stanford University
- Study coordinator: Feyaerts, Dorien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.