Understanding the immune environment in benign prostatic hyperplasia

Immune microenvironment in BPH pathogenesis

NIH-funded research Stanford University · NIH-10899756

This study is looking at how the immune system plays a role in benign prostatic hyperplasia (BPH), a common condition in older men that causes urinary problems, to find new ways to treat it more effectively.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10899756 on NIH RePORTER

What this research studies

This research investigates how the immune system contributes to benign prostatic hyperplasia (BPH), a condition that affects many older men and causes urinary issues. By analyzing the immune response and gene expression in prostate tissue, the study aims to identify specific biological pathways involved in BPH. The researchers will compare immune responses in BPH patients to those in healthy individuals to uncover potential new treatment targets. This approach could lead to more effective therapies that directly address the underlying causes of BPH rather than just alleviating symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are men diagnosed with benign prostatic hyperplasia, particularly those experiencing significant urinary symptoms.

Not a fit: Patients with prostate conditions other than benign prostatic hyperplasia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of targeted treatments that improve the quality of life for men suffering from BPH.

How similar studies have performed: Previous research has shown promise in understanding immune mechanisms in other prostate conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.