Understanding the human virome's role in the oral-gut-brain connection
Official title: Human Virome Characterization Center for the Oral-Gut-Brain Axis
Funded at University of California Los Angeles · NIH-10990433 · Data updated 2026-11-12
This study is looking at the viruses in our bodies, especially how they connect our mouth, gut, and brain, to help us understand how these tiny organisms affect our health, which could lead to better ways to manage related health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $565,330 |
| NIH project number | 1U54AG089335-01 |
| Project ID | NIH-10990433 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions related to the oral-gut-brain axis, such as gastrointestinal disorders or neurological conditions.
✕Less likely to help
Patients with conditions unrelated to the microbiome or the oral-gut-brain axis may not receive any benefit from this research.
What this research studies
This research focuses on characterizing the human virome, which includes the viruses present in our bodies, particularly in relation to the oral-gut-brain axis. By utilizing advanced bioinformatics tools and artificial intelligence, the project aims to analyze microbiome data and improve our understanding of how these microorganisms affect health. Patients may benefit from insights gained through this research, which could lead to better management of conditions linked to the microbiome. The research will involve collaboration among experts in microbiology, virology, and data analysis to ensure comprehensive data management and dissemination.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes by enhancing our understanding of the microbiome's influence on various health conditions.
How similar studies have gone: Previous research has shown success in understanding the microbiome's role in health, indicating that this approach has potential for meaningful advancements.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Javornik Cregeen, Sara — University of California Los Angeles
- Study coordinator: Javornik Cregeen, Sara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.