Understanding the HIV reservoir and its changes over time
High-Definition Characterization of the Persistence and Perturbation of the HIV Reservoir: Project 1
This study is looking at how HIV hides in certain cells in the body, even when you're on treatment, to help find better ways to manage the virus, and we're inviting patients to share their samples and experiences to help us learn more.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11080766 on NIH RePORTER |
What this research studies
This research focuses on the detailed analysis of the HIV reservoir, which is a collection of cells in the body that harbor the virus even when patients are on treatment. By collecting and analyzing participant samples, the project aims to understand how these reservoirs persist and change, which is crucial for developing more effective treatments. The research involves collaboration with the AIDS Clinical Trials Group to ensure comprehensive data collection and participant engagement. Patients may be asked to provide samples and participate in discussions about their treatment experiences.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently receiving antiretroviral therapy.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing HIV and potentially eradicating the virus from the body.
How similar studies have performed: Previous research has shown promise in understanding HIV reservoirs, indicating that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Li, Jonathan — Brigham and Women's Hospital
- Study coordinator: Li, Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.