Understanding the HIV-1 virus and its interactions for better treatments and vaccines
Multiscale Computational Microscopy of HIV-1
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10884393
This study is looking at how the HIV-1 virus interacts with human cells to help create better vaccines and find new treatments for people living with HIV.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10884393 on ClinicalTrials.gov |
What this research studies
This research investigates the HIV-1 virus, which causes AIDS, by using advanced computational techniques to simulate the virus's envelope protein and its interactions with human cells. By employing all-atom molecular dynamics simulations, the team aims to uncover details about the virus's structure and behavior that are not visible through traditional experimental methods. This approach will help in designing better vaccines and identifying potential drug targets to combat HIV-1 effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV or those at high risk of HIV infection who are seeking new treatment options.
Not a fit: Patients who are not affected by HIV or those who have already achieved viral suppression may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for HIV-1, ultimately reducing infection rates and improving patient outcomes.
How similar studies have performed: Previous research using computational modeling has shown promise in understanding viral structures and developing vaccines, indicating that this approach could yield valuable insights.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AMARO, ROMMIE E — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: AMARO, ROMMIE E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus